Hypertension: Shall We Focus on Adipose Tissue?
نویسندگان
چکیده
منابع مشابه
Hypertension: shall we focus on adipose tissue?
Adipose tissue is an active endocrine organ that produces substances having local and systemic actions on blood vessels, kidneys, and the heart. Leptin, adiponectin, resistin, angiotensin II, adipsin, TNF, IGF-1, plasminogen-activator inhibitor 1, and prostaglandins compose an incomplete list.1 Resistin, an adipokine belonging to the cysteine-rich secretory protein family, was described as an a...
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BACKGROUND Adipose tissue (AT) is involved in several physiological functions, including metabolic regulation, energy storage, and endocrine functions. OBJECTIVES In this review we examined the evidence that an additional function of AT is to modulate persistent organic pollutant (POP) toxicity through several mechanisms. METHODS We reviewed the literature on the interaction of AT with POPs...
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Most blood vessels are surrounded by a variable amount of adventitial adipose tissue, perivascular adipose tissue (PVAT), which was originally thought to provide mechanical support for the vessel. It is now known that PVAT secretes a number of bioactive substances including vascular endothelial growth factor, tumor necrosis factor-alpha (TNF-α), leptin, adiponectin, insulin-like growth factor, ...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2010
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2010050524